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Apoptosis MeSH Descriptor Data 2022


MeSH Heading
Apoptosis
Tree Number(s)
G04.146.954.035
Unique ID
D017209
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D017209
Annotation
general or unspecified, note specifics
Scope Note
A regulated cell death mechanism characterized by distinctive morphologic changes in the nucleus and cytoplasm, including the endonucleolytic cleavage of genomic DNA, at regularly spaced, internucleosomal sites, i.e., DNA FRAGMENTATION. It is genetically programmed and serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.
Entry Term(s)
Apoptosis, Extrinsic Pathway
Apoptosis, Intrinsic Pathway
Caspase-Dependent Apoptosis
Classic Apoptosis
Classical Apoptosis
Programmed Cell Death
Programmed Cell Death, Type I
NLM Classification #
QU 375
Previous Indexing
Cell Survival (1972-1992)
See Also
CARD Signaling Adaptor Proteins
Caspases
Cellular Apoptosis Susceptibility Protein
Death Domain Receptor Signaling Adaptor Proteins
Genes, Transgenic, Suicide
In Situ Nick-End Labeling
Necrosis
Public MeSH Note
93
History Note
93
Date Established
1993/01/01
Date of Entry
1992/05/07
Revision Date
2021/06/30
Apoptosis Preferred
Apoptosis, Intrinsic Pathway Narrower
Apoptosis, Extrinsic Pathway Narrower
Caspase-Dependent Apoptosis Narrower
Programmed Cell Death Narrower
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