MeSH Browser

MeSH Heading: Parthanatos
Tree Number(s): G04.146.954.750
Unique ID: D000079323
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000079323
Scope Note: A type of regulated cell death initiated by hyperactivation of POLY (ADP-RIBOSE) POLYMERASE-1 (PARP-1) as a consequence of DNA DAMAGE; OXIDATIVE STRESS; HYPOXIA; HYPOGLYCEMIA; or INFLAMMATION. This leads to DNA FRAGMENTATION and CHROMATIN condensation.
Entry Term(s): PARP-1-Dependent Cell Death; PARP-Dependent Cell Death
Previous Indexing: Cell Death (2008-2019)
Public MeSH Note: 2020
History Note: 2020
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2019/05/30

Allowable Qualifiers: drug effects (DE)

genetics (GE)

immunology (IM)

physiology (PH)

radiation effects (RE)

Parthanatos MeSH Descriptor Data 2025