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Necroptosis MeSH Descriptor Data 2022


MeSH Heading
Necroptosis
Tree Number(s)
G04.146.954.500
Unique ID
D000079302
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000079302
Annotation
do not confuse with NECROSIS the pathological process
Scope Note
A form of regulated cell death initiated by perturbations of extracellular or intracellular homeostasis that trigger a specific cell death pathway involving the activation of RIPK3 and MLKL (mixed lineage kinase domain like pseudokinase). Morphological changes include cytoplasmic and organellar swelling, rupture of the PLASMA MEMBRANE, and CHROMATIN CONDENSATION.
Previous Indexing
Necrosis (2005-2019)
Public MeSH Note
2020
History Note
2020
Date Established
2020/01/01
Date of Entry
2019/07/08
Revision Date
2019/05/30
Necroptosis Preferred
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