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PDZ Domains MeSH Descriptor Data 2022


MeSH Heading
PDZ Domains
Tree Number(s)
G02.111.570.820.709.275.750.500.500
Unique ID
D054731
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D054731
Scope Note
Protein interaction domains of about 70-90 amino acid residues, named after a common structure found in PSD-95, Discs Large, and Zona Occludens 1 proteins. PDZ domains are involved in the recruitment and interaction of proteins, and aid the formation of protein scaffolds and signaling networks. This is achieved by sequence-specific binding between a PDZ domain in one protein and a PDZ motif in another protein.
Entry Term(s)
DHR Domains
DLG Homology Repeats Domains
GLGF Repeats Domains
PDZ Interaction Domains
PSD95-DLG-ZO1 Domains
Public MeSH Note
2008
History Note
2008
Date Established
2008/01/01
Date of Entry
2007/07/09
Revision Date
2016/05/31
PDZ Domains Preferred
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