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PHD Zinc Fingers MeSH Descriptor Data 2022


MeSH Heading
PHD Zinc Fingers
Tree Number(s)
G02.111.570.820.709.275.500.985.438
Unique ID
D000075925
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000075925
Scope Note
Zinc finger domains of approximately 50 to 80 amino acids in length that are characterized by a conserved Cysteine(3)-Histidine-Cysteine(4) amino acid motif which coordinates binding of two zinc ions. They are similar structurally to RING FINGER DOMAINS, with a globular fold topology of two BETA-SHEETS and an ALPHA-HELIX. PHD fingers occur in many proteins that function in chromatin-mediated gene expression and EPIGENETICS such as POLYCOMB-GROUP PROTEINS.
Entry Term(s)
PHD Domains
PHD Finger Domain
PHD Fingers
PHD Motif
PHD Motifs
PHD Zinc Finger
Previous Indexing
Amino Acid Sequence (1995-2017)
Molecular Sequence Data (1995-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/06/29
PHD Zinc Fingers Preferred
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