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Thyroid Nuclear Factor 1 MeSH Descriptor Data 2022


MeSH Heading
Thyroid Nuclear Factor 1
Tree Number(s)
D12.776.260.400.871
D12.776.660.823
D12.776.930.888
Unique ID
D000074482
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074482
Scope Note
A homeobox protein and transcription factor that localizes to the cell nucleus where it activates expression of thyroid specific genes such as THYROGLOBULIN and the THYROTROPIN RECEPTOR. It is critical for maintaining thyroid tissue in a differentiated state and also plays a role in lung development. Mutations in the NKX2-1 gene are associated with CHOREA, BENIGN HEREDITARY.
Entry Term(s)
Homeobox Protein Nkx-2.1
NK2 Homeobox 1 Protein
TITF-1 Protein
TITF1 Protein
TTF-1 Thyroid Nuclear Factor
Thyroid Transcription Factor 1
Thyroid-Specific Enhancer-Binding Protein
Registry Number
0
Public MeSH Note
2018; THYROID NUCLEAR FACTOR 1 was indexed under NUCLEAR PROTEINS and TRANSCRIPTION FACTORS 1990-2017
History Note
2018 (1990)
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2017/04/06
Thyroid Nuclear Factor 1 Preferred
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