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AIRE Protein MeSH Descriptor Data 2024

MeSH Heading
AIRE Protein
Tree Number(s)
Unique ID
RDF Unique Identifier
Scope Note
A transcriptional regulator primarily expressed in medullary thymic epithelial cells. It plays an important role in immunity by regulating the expression of a wide array of SELF-ANTIGENS and negative selection of autoreactive T-cells in the thymus. Deficiency in this protein induces a rare autosomal-recessive disease called AUTOIMMUNE POLYENDOCRINOPATHY-CANDIDIASIS-ECTODERMAL DYSTROPHY.
Entry Term(s)
APECED Protein
Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Protein
Autoimmune Regulator Protein
Public MeSH Note
2024; AIRE PROTEIN was indexed under TRANSCRIPTION FACTORS 1997-2023
History Note
2024 (1997)
Date Established
Date of Entry
Revision Date
AIRE Protein Preferred
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