- Concept UI
- M000762772
- Registry Numbers
- 0
- Scope Note
- A transcriptional regulator primarily expressed in medullary thymic epithelial cells. It plays an important role in immunity by regulating the expression of a wide array of SELF-ANTIGENS and negative selection of autoreactive T-cells in the thymus. Deficiency in this protein induces a rare autosomal-recessive disease called AUTOIMMUNE POLYENDOCRINOPATHY-CANDIDIASIS-ECTODERMAL DYSTROPHY.
- Terms
-
AIRE Protein
Preferred Term
Term UI
T001133091
Date02/21/2023
LexicalTag
NON
ThesaurusID
NLM (2024)
-
APECED Protein
Term UI
T001133093
Date02/21/2023
LexicalTag
ABX
ThesaurusID
NLM (2024)
-
Autoimmune Regulator Protein
Term UI
T001133095
Date02/21/2023
LexicalTag
NON
ThesaurusID
NLM (2024)
-
Autoimmune Polyendocrinopathy Candidiasis Ectodermal Dystrophy Protein
Term UI
T001133145
Date02/22/2023
LexicalTag
NON
ThesaurusID
NLM (2024)