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I-kappa B Proteins MeSH Descriptor Data 2025


MeSH Heading
I-kappa B Proteins
Tree Number(s)
D12.644.360.365
D12.776.260.420
D12.776.476.381
D12.776.930.326
Unique ID
D020672
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020672
Scope Note
A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.
Entry Term(s)
I kappa B
I-kappa B
IkB DNA-Binding Proteins
Registry Numbers
0
Previous Indexing
DNA-Binding Proteins (1998-1999)
Proto-Oncogene Proteins (1993-1998)
See Also
I-kappa B Kinase
NF-kappa B
Proto-Oncogene Proteins c-rel
Public MeSH Note
2000; see I KAPPA B 2000-2005, I KAPPA B PROTEINS was indexed under PROTO-ONCOGENE PROTEINS 1993-1998 & DNA-BINDING PROTEINS 1998-1999
History Note
2006(2000)
Date Established
2000/01/01
Date of Entry
1999/11/04
Revision Date
2017/06/30
I-kappa B Proteins Preferred
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