MeSH Browser

MeSH Heading: Activating Transcription Factor 6
Tree Number(s): D12.644.360.011; D12.776.260.108.061.968; D12.776.476.011; D12.776.930.127.061.968
Unique ID: D051702
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051702
Scope Note: One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protein in the ENDOPLASMIC RETICULUM. In response to endoplasmic reticulum stress it translocates to the GOLGI APPARATUS. It is activated by PROTEASES and then moves to the CELL NUCLEUS to regulate GENETIC TRANSCRIPTION of GENES involved in the unfolded protein response.
Entry Term(s): ATF6 Transcription Factor
Public MeSH Note: 2006; ACTIVATING TRANSCRIPTION FACTOR 6 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1997-2005
History Note: 2006(1997)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2015/11/23

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toxicity (TO)

ultrastructure (UL)

urine (UR)

Activating Transcription Factor 6 MeSH Descriptor Data 2024