- Concept UI
- M0280604
- Registry Numbers
- 0
- Scope Note
- One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protein in the ENDOPLASMIC RETICULUM. In response to endoplasmic reticulum stress it translocates to the GOLGI APPARATUS. It is activated by PROTEASES and then moves to the CELL NUCLEUS to regulate GENETIC TRANSCRIPTION of GENES involved in the unfolded protein response.
- Terms
-
Activating Transcription Factor 6
Preferred Term
Term UI
T632405
Date03/04/2005
LexicalTag
NON
ThesaurusID
NLM (2006)
-
ATF6 Transcription Factor
Term UI
T635085
Date04/04/2005
LexicalTag
ABX
ThesaurusID
NLM (2006)