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Activating Transcription Factor 6 MeSH Descriptor Data 2022


MeSH Heading
Activating Transcription Factor 6
Tree Number(s)
D12.644.360.011
D12.776.260.108.061.968
D12.776.476.011
D12.776.930.127.061.968
Unique ID
D051702
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051702
Scope Note
One of the BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS that is synthesized as a membrane-bound protein in the ENDOPLASMIC RETICULUM. In response to endoplasmic reticulum stress it translocates to the GOLGI APPARATUS. It is activated by PROTEASES and then moves to the CELL NUCLEUS to regulate GENETIC TRANSCRIPTION of GENES involved in the unfolded protein response.
Entry Term(s)
ATF6 Transcription Factor
Registry Number
0
Public MeSH Note
2006; ACTIVATING TRANSCRIPTION FACTOR 6 was indexed under DNA-BINDING PROTEINS & TRANSCRIPTION FACTORS 1997-2005
History Note
2006(1997)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2015/11/23
Activating Transcription Factor 6 Preferred
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