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Myristoylated Alanine-Rich C Kinase Substrate MeSH Descriptor Data 2025
A membrane and ACTIN CYTOSKELETON associated, N-terminal myristoylated protein that binds CALMODULIN and is a prominent substrate for PROTEIN KINASE C. Both phosphorylation and poly(ADP)-ribosylation inhibit its F-ACTIN crosslinking activity; phosphorylation also causes MARCKS to relocate from the membrane to cytoplasm.
Entry Term(s)
ACAMP-81
MARCKS Protein
Registry Numbers
125267-21-2
Public MeSH Note
2018; MYRISTOYLATED ALANINE-RICH C KINASE SUBSTRATE was indexed under MEMBRANE PROTEINS and INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS 1989-2017
A membrane and ACTIN CYTOSKELETON associated, N-terminal myristoylated protein that binds CALMODULIN and is a prominent substrate for PROTEIN KINASE C. Both phosphorylation and poly(ADP)-ribosylation inhibit its F-ACTIN crosslinking activity; phosphorylation also causes MARCKS to relocate from the membrane to cytoplasm.