MeSH Browser

MeSH Heading: Myristoylated Alanine-Rich C Kinase Substrate
Tree Number(s): D05.750.078.730.556; D12.644.360.537; D12.776.157.142.375; D12.776.157.687.496; D12.776.220.525.556; D12.776.476.539; D12.776.543.637; D12.776.660.720.496
Unique ID: D000076250
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000076250
Scope Note: A membrane and ACTIN CYTOSKELETON associated, N-terminal myristoylated protein that binds CALMODULIN and is a prominent substrate for PROTEIN KINASE C. Both phosphorylation and poly(ADP)-ribosylation inhibit its F-ACTIN crosslinking activity; phosphorylation also causes MARCKS to relocate from the membrane to cytoplasm.
Entry Term(s): ACAMP-81; MARCKS Protein
Registry Numbers: 125267-21-2
Public MeSH Note: 2018; MYRISTOYLATED ALANINE-RICH C KINASE SUBSTRATE was indexed under MEMBRANE PROTEINS and INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS 1989-2017
History Note: 2018 (1989)
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/29

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0166716
Registry Numbers: 125267-21-2
Scope Note: A membrane and ACTIN CYTOSKELETON associated, N-terminal myristoylated protein that binds CALMODULIN and is a prominent substrate for PROTEIN KINASE C. Both phosphorylation and poly(ADP)-ribosylation inhibit its F-ACTIN crosslinking activity; phosphorylation also causes MARCKS to relocate from the membrane to cytoplasm.
Terms: Myristoylated Alanine-Rich C Kinase Substrate Preferred Term
Term UI T000925929
Date06/01/2017
LexicalTag NON
ThesaurusID NLM (1989); MARCKS Protein
Term UI T000925930
Date06/01/2017
LexicalTag ACX
ThesaurusID NLM (1989); ACAMP-81
Term UI T196719
Date01/01/1955
LexicalTag ABB
ThesaurusID NLM (1989)

Myristoylated Alanine-Rich C Kinase Substrate MeSH Descriptor Data 2024