MeSH Browser

MeSH Heading: Tensins
Tree Number(s): D05.750.078.730.719; D12.776.220.525.719
Unique ID: D000070876
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000070876
Scope Note: A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.
Entry Term(s): Tensin
Public MeSH Note: 2017; TENSINS was indexed under MICROFILAMENT PROTEINS (1992-2016)
History Note: 2017 (1992)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2016/02/26

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Tensins MeSH Descriptor Data 2024