- Concept UI
- M0201606
- Registry Numbers
- 0
- Scope Note
- A family of multidomain microfilament proteins that bind ACTIN FILAMENTS and INTEGRINS at FOCAL ADHESIONS. They generally consist of an N-terminal domain with homology to PHOSPHOTYROSINE PHOSPHATASE, a C2 DOMAIN; unique central regions rich in PROLINE; ALANINE; GLYCINE; and SERINE; an SH2 DOMAIN; and a C-terminal phosphotyrosine-binding region. They are involved in CELL MIGRATION; CELL ADHESION; SIGNAL TRANSDUCTION; and reorganization of the CYTOSKELETON.
- Terms
-
Tensins
Preferred Term
Term UI
T000891731
Date12/07/2015
LexicalTag
NON
ThesaurusID
NLM (2007)
-
Tensin
Term UI
T000891732
Date12/07/2015
LexicalTag
NON
ThesaurusID
NLM (1992)