MeSH Browser

MeSH Heading: Formins
Tree Number(s): D05.750.078.730.333; D12.776.220.525.333
Unique ID: D000080865
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000080865
Scope Note: A family of multidomain microfilament proteins associated with ACTIN FILAMENTS. They generally have multiple Formin-Homology domains (e.g., FH2 domain) and additionally have a RhoGTPase-binding domain and a diaphanous inhibitory domain. Formins and homologs are involved in actin reorganization.
Entry Term(s): DIAPH Protein 1; DIAPH Protein 2; DIAPH Proteins; Diaphanous-Related Formin Homology Proteins; Diaphanous-Related Formins; FMN Protein 1; FMN Protein 2; FMN Proteins; Formin; Formin 1 Protein; Formin 2 Protein; Formin Homology Proteins
Previous Indexing: Microfilament Proteins (1992-2019)
Public MeSH Note: 2020
History Note: 2020
Date Established: 2020/01/01
Date of Entry: 2019/07/08
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000648512
Scope Note: A family of multidomain microfilament proteins associated with ACTIN FILAMENTS. They generally have multiple Formin-Homology domains (e.g., FH2 domain) and additionally have a RhoGTPase-binding domain and a diaphanous inhibitory domain. Formins and homologs are involved in actin reorganization.
Terms: Formins Preferred Term
Term UI T000955033
Date04/09/2019
LexicalTag NON
ThesaurusID NLM (2020); Formin
Term UI T000996515
Date11/15/2019
LexicalTag NON
ThesaurusID NLM (2021); FMN Proteins
Term UI T000955110
Date04/10/2019
LexicalTag ABX
ThesaurusID NLM (2020); Formin Homology Proteins
Term UI T000955073
Date04/10/2019
LexicalTag NON
ThesaurusID NLM (2020)

Formins MeSH Descriptor Data 2024