MeSH Browser

MeSH Heading: Calponins
Tree Number(s): D05.750.078.730.266; D12.776.157.125.123; D12.776.210.500.187; D12.776.220.525.268
Unique ID: D000096985
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000096985
Scope Note: A family of actin binding proteins mostly in smooth muscle. Calponins include most abundant alpha-calponin (h1 or basic); beta-calponin; neutral calponin (h2 calponin); acidic calponin, SM22, and transgelin. Calponin family members have N-terminal single Calponin Homology (CH) domain and multiple C-terminus 23-amino acids long calponin-like repeats called CLICK-23. Calponins participate in modulation of smooth muscle contraction by binding to ACTINS (F- and G-Actins), CALMODULIN and TROPOMYSIN.
Entry Term(s): Calponin; Calponin Family Proteins
Registry Number: 0
Previous Indexing: Microfilament Proteins (1990-2023)
Public MeSH Note: 2024
History Note: 2024
Date Established: 2024/01/01
Date of Entry: 2023/07/26
Revision Date: 2023/06/07

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M000762830
Registry Number: 0
Scope Note: A family of actin binding proteins mostly in smooth muscle. Calponins include most abundant alpha-calponin (h1 or basic); beta-calponin; neutral calponin (h2 calponin); acidic calponin, SM22, and transgelin. Calponin family members have N-terminal single Calponin Homology (CH) domain and multiple C-terminus 23-amino acids long calponin-like repeats called CLICK-23. Calponins participate in modulation of smooth muscle contraction by binding to ACTINS (F- and G-Actins), CALMODULIN and TROPOMYSIN.
Terms: Calponins Preferred Term
Term UI T001133085
Date02/21/2023
LexicalTag NON
ThesaurusID NLM (2024); Calponin Family Proteins
Term UI T001133086
Date02/21/2023
LexicalTag NON
ThesaurusID NLM (2024); Calponin
Term UI T001135674
Date03/30/2023
LexicalTag NON
ThesaurusID NLM (2024)

Calponins MeSH Descriptor Data 2024