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membrane proteins; from the Greek word for anchor with ref to their role in attachment of the cytoskeleton; /drug eff/ultrastruct permitted
Scope Note
A family of membrane-associated proteins responsible for the attachment of the cytoskeleton. Erythrocyte-related isoforms of ankyrin attach the SPECTRIN cytoskeleton to a transmembrane protein (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE) in the erythrocyte plasma membrane. Brain-related isoforms of ankyrin also exist.
Entry Term(s)
Ankyrin
Registry Numbers
0
Previous Indexing
Blood Proteins (1979-1992)
Membrane Proteins (1979-1992)
Public MeSH Note
93; ANKYRIN was indexed under BLOOD PROTEINS & MEMBRANE PROTEINS 1979-92
A family of membrane-associated proteins responsible for the attachment of the cytoskeleton. Erythrocyte-related isoforms of ankyrin attach the SPECTRIN cytoskeleton to a transmembrane protein (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE) in the erythrocyte plasma membrane. Brain-related isoforms of ankyrin also exist.