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Presenilins MeSH Descriptor Data 2023


MeSH Heading
Presenilins
Tree Number(s)
D12.776.543.696
Unique ID
D053763
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053763
Scope Note
Integral membrane proteins and essential components of the gamma-secretase complex that catalyzes the cleavage of membrane proteins such as NOTCH RECEPTORS and AMYLOID BETA-PEPTIDES precursors. Mutations of presenilins lead to presenile ALZHEIMER DISEASE with onset before age 65 years.
Entry Term(s)
Presenilin
Registry Number
0
Previous Indexing
Alzheimer Disease (1995-2006)
Membrane Proteins (1995-2006)
Public MeSH Note
2007
History Note
2007
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2010/06/25
Presenilins Preferred
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