NLM Logo

Protoporphyrinogen Oxidase MeSH Descriptor Data 2023


MeSH Heading
Protoporphyrinogen Oxidase
Tree Number(s)
D08.811.682.660.600
D12.776.543.697
Unique ID
D050768
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D050768
Scope Note
A membrane-bound flavoenzyme that catalyzes the oxygen-dependent aromatization of protoporphyrinogen IX (Protogen) to protoporphyrin IX (Proto IX). It is the last enzyme of the common branch of the HEME and CHLOROPHYLL pathways in plants, and is the molecular target of diphenyl ether-type herbicides. VARIEGATE PORPHYRIA is an autosomal dominant disorder associated with deficiency of protoporphyrinogen oxidase.
Entry Term(s)
Protoporphyrinogen Dehydrogenase
Protoporphyrinogen IX Oxidase
Protoporphyrinogenase
Protox
Registry Number
EC 1.3.3.4
Previous Indexing
Oxidoreductases (1993-2003)
Oxidoreductases Acting on CH-CH Group Donors (2004-2005)
Porphyrins (1975-1976)
Protoporphyrins (1975-1982)
Public MeSH Note
2006; PROTOPORPHYRINOGEN OXIDASE was indexed under OXIDOREDUCTASES ACTING ON CH-CH GROUP DONORS 2004-2005, under OXIDOREDUCTASES 1993-2003, under PORPHYRINS 1975-1976, and under PROTOPORPHYRINS 1975-1982
History Note
2006(1975)
Entry Combination
deficiency:Porphyria, Variegate
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2009/07/15
Protoporphyrinogen Oxidase Preferred
page delivered in 0.216s