MeSH Browser

MeSH Heading: Porphyria, Variegate
Tree Number(s): C06.552.830.625; C16.320.850.742.625; C17.800.827.742.625; C18.452.811.400.625
Unique ID: D046350
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D046350
Scope Note: An autosomal dominant porphyria that is due to a deficiency of protoporphyrinogen oxidase (EC 1.3.3.4) in the LIVER, the seventh enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features include both neurological symptoms and cutaneous lesions. Patients excrete increased levels of porphyrin precursors, COPROPORPHYRINS and protoporphyrinogen.
Entry Term(s): Porphyria Variegata; Porphyria Variegate; Porphyria, South African Type; Ppox Deficiency; Protoporphyrinogen Oxidase Deficiency; Variegate Porphyria
Previous Indexing: Porphyria (1964-2004); Porphyria, Hepatic (1993-2004)
Public MeSH Note: 2005; see PORPHYRIA, HEPATIC 1993-2004
History Note: 2005; use PORPHYRIA, HEPATIC 1993-2004
Date Established: 2005/01/01
Date of Entry: 2004/07/15
Revision Date: 2020/02/28

Allowable Qualifiers: blood (BL)

cerebrospinal fluid (CF)

chemically induced (CI)

classification (CL)

complications (CO)

congenital (CN)

diagnosis (DI)

diagnostic imaging (DG)

diet therapy (DH)

drug therapy (DT)

economics (EC)

embryology (EM)

enzymology (EN)

epidemiology (EP)

ethnology (EH)

etiology (ET)

genetics (GE)

history (HI)

immunology (IM)

metabolism (ME)

microbiology (MI)

mortality (MO)

nursing (NU)

parasitology (PS)

pathology (PA)

physiopathology (PP)

prevention & control (PC)

psychology (PX)

radiotherapy (RT)

rehabilitation (RH)

surgery (SU)

therapy (TH)

urine (UR)

veterinary (VE)

virology (VI)

Concept UI: M0025972
Scope Note: An autosomal dominant porphyria that is due to a deficiency of protoporphyrinogen oxidase (EC 1.3.3.4) in the LIVER, the seventh enzyme in the 8-enzyme biosynthetic pathway of HEME. Clinical features include both neurological symptoms and cutaneous lesions. Patients excrete increased levels of porphyrin precursors, COPROPORPHYRINS and protoporphyrinogen.
Terms: Porphyria, Variegate Preferred Term
Term UI T051034
Date10/01/1991
LexicalTag NON
ThesaurusID NLM (1993); Variegate Porphyria
Term UI T551554
Date09/24/2003
LexicalTag NON
ThesaurusID; Porphyria, South African Type
Term UI T001000227
Date12/05/2019
LexicalTag NON
ThesaurusID; Ppox Deficiency
Term UI T812054
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Porphyria Variegata
Term UI T812055
Date11/15/2011
LexicalTag NON
ThesaurusID OMIM (2013); Protoporphyrinogen Oxidase Deficiency
Term UI T551555
Date09/24/2003
LexicalTag NON
ThesaurusID; Porphyria Variegate
Term UI T752481
Date06/08/2009
LexicalTag NON
ThesaurusID

Porphyria, Variegate MeSH Descriptor Data 2024