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15-Oxoprostaglandin 13-Reductase MeSH Descriptor Data 2025
(5Z)-(15S)-11 alpha-Hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta(13)-oxidoreductase. An enzyme active in prostaglandin E and F catabolism. It catalyzes the reduction of the double bond at the 13-14 position of the 15-ketoprostaglandins and uses NADPH as cofactor. EC 1.3.1.48.
Entry Version
OXOPG REDUCTASE
Entry Term(s)
15-Ketoprostaglandin delta 13-Reductase
Prostaglandin delta-13-Reductase
Prostaglandin-13,14-Reductase
delta 13-15-Ketoprostaglandin Reductase
delta-13-PG-Reductase
Registry Numbers
EC 1.3.1.48
Previous Indexing
Oxidoreductases (1966-1977)
Prostaglandins (1966-1977)
specific prostaglandin (1975-1977)
Public MeSH Note
94; was PROSTAGLANDIN-13,14-REDUCTASE 1978-93 (see under OXIDOREDUCTASES 1978-90); DELTA 13-15-KETOPROSTAGLANDIN REDUCTASE was indexed under PROSTAGLANDIN-13,14-REDUCTASE 1981-93 and OXIDOREDUCTASES & PROSTAGLANDINS 1976-80; PROSTAGLANDIN DELTA 13 REDUCTASE was indexed under OXIDOREDUCTASES 1981-93
Online Note
use 15-OXOPROSTAGLANDIN 13-REDUCTASE to search PROSTAGLANDIN-13,14-REDUCTASE 1978-93; use 15-OXOPROSTAGLANDIN 13-REDUCTASE (NM) to search DELTA 13-15-KETOPROSTAGLANDIN REDUCTASE 1980-93 & PROSTAGLANDIN DELTA 13 REDUCTASE 1981-93
History Note
94; was PROSTAGLANDIN-13,14-REDUCTASE 1978-93 (see under OXIDOREDUCTASES 1978-90); DELTA 13-15-KETOPROSTAGLANDIN REDUCTASE was (NM) 1976-93; PROSTAGLANDIN DELTA 13 REDUCTASE was (NM) 1981-93
(5Z)-(15S)-11 alpha-Hydroxy-9,15-dioxoprostanoate:NAD(P)+ delta(13)-oxidoreductase. An enzyme active in prostaglandin E and F catabolism. It catalyzes the reduction of the double bond at the 13-14 position of the 15-ketoprostaglandins and uses NADPH as cofactor. EC 1.3.1.48.