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An enzyme that in the course of pyrimidine biosynthesis, catalyzes the oxidation of dihydro-orotic acid to orotic acid utilizing oxygen as the electron acceptor. This enzyme is a flavoprotein which contains both FLAVIN-ADENINE DINUCLEOTIDE and FLAVIN MONONUCLEOTIDE as well as iron-sulfur centers. EC 1.3.3.1.
Entry Term(s)
Dihydro-Orotate Oxidase
Registry Numbers
EC 1.3.98.1
CAS Type 1 Name
(S)-Dihydroorotate:oxygen oxidoreductase
Previous Indexing
Orotic Acid (1966-1976)
Oxidoreductases (1966-1976)
Public MeSH Note
94; was DIHYDRO-OROTATE OXIDASE 1977-93 (see under OXIDOREDUCTASES 1977-90); DIHYDRO-OROTATE DEHYDROGENASE & OROTATE REDUCTASE were see DIHYDRO-OROTATE OXIDASE 1977-93
Online Note
use DIHYDROOROTATE OXIDASE to search DIHYDRO-OROTATE OXIDASE, DIHYDRO-OROTATE DEHYDROGENASE & OROTATE REDUCTASE 1977-93
History Note
94; was DIHYDRO-OROTATE OXIDASE 1977-93 (see under OXIDOREDUCTASES 1977-90); DIHYDRO-OROTATE DEHYDROGENASE & OROTATE REDUCTASE were see DIHYDRO-OROTATE OXIDASE 1977-93
An enzyme that in the course of pyrimidine biosynthesis, catalyzes the oxidation of dihydro-orotic acid to orotic acid utilizing oxygen as the electron acceptor. This enzyme is a flavoprotein which contains both FLAVIN-ADENINE DINUCLEOTIDE and FLAVIN MONONUCLEOTIDE as well as iron-sulfur centers. EC 1.3.3.1.