A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein contains no lipids or carbohydrates, is the predominant species of peripheral erythrocyte membrane proteins, and exists as a fibrous coating on the inner, cytoplasmic surface of the membrane.
Entry Term(s)
alpha-Spectrin
beta-Spectrin
Registry Number
12634-43-4
CAS Type 1 Name
Spectrins
Previous Indexing
Blood Proteins (1966-1976)
Cell Membrane (1966-1975)
Erythrocytes (1966-1975)
Public MeSH Note
84; was see under MEMBRANE PROTEINS 1978-83, was see under BLOOD PROTEINS 1977
History Note
84(77); was see under MEMBRANE PROTEINS 1978-83, was see under BLOOD PROTEINS 1977
A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein contains no lipids or carbohydrates, is the predominant species of peripheral erythrocyte membrane proteins, and exists as a fibrous coating on the inner, cytoplasmic surface of the membrane.
