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A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton.
Entry Term(s)
Band 2 Protein
Platelet Protein p235
Registry Numbers
0
Previous Indexing
Blood Proteins (1984-1986)
Contractile Proteins (1982-1986)
Cytoskeletal Proteins (1985-1991)
Muscle Proteins (1984-1986)
Public MeSH Note
92; TALIN was indexed under CYTOSKELETAL PROTEINS 1987-91, under MUSCLE PROTEINS 1984-86 & under CONTRACTILE PROTEINS 1982-86
A 235-kDa cytoplasmic protein that is also found in platelets. It has been localized to regions of cell-substrate adhesion. It binds to INTEGRINS; VINCULIN; and ACTINS and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton.