NLM Logo

Ku Autoantigen MeSH Descriptor Data 2023


MeSH Heading
Ku Autoantigen
Tree Number(s)
D08.811.277.040.025.159.155
D08.811.399.340.155
D12.776.157.687.493
D12.776.260.525
D12.776.660.625.625
D12.776.660.720.493
D23.050.290.625
Unique ID
D000072200
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072200
Scope Note
An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.
Entry Term(s)
G22P1 Antigen
Ku Antigen
Ku Autoantigen, 70 kDa
Ku Autoantigen, 80 kDa
Ku Heterodimer
Ku Protein
Ku70 Antigen
Ku80 Antigen
X-ray Repair Cross-Complementing Protein 5
X-ray Repair Cross-Complementing Protein 6
XRCC5 Protein
XRCC6 Protein
Registry Number
EC 4.2.99.-
Related Numbers
EC 3.6.4.12
Public MeSH Note
2017; KU AUTOANTIGEN was indexed under DNA-BINDING PROTEINS and ANTIGENS, NUCLEAR 2003-2016; and under ANTIGENS, SURFACE 1986-1991 and NUCLEAR PROTEINS 1985-2003
History Note
2017 (1986)
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2017/05/24
Ku Autoantigen Preferred
Ku80 Antigen Narrower
Ku70 Antigen Narrower
page delivered in 0.209s