MeSH Browser

MeSH Heading: Ku Autoantigen
Tree Number(s): D08.811.277.040.025.159.155; D08.811.399.340.155; D12.776.157.687.493; D12.776.260.525; D12.776.660.625.625; D12.776.660.720.493; D23.050.290.625
Unique ID: D000072200
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000072200
Scope Note: An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.
Entry Term(s): G22P1 Antigen; Ku Antigen; Ku Autoantigen, 70 kDa; Ku Autoantigen, 80 kDa; Ku Heterodimer; Ku Protein; Ku70 Antigen; Ku80 Antigen; X-ray Repair Cross-Complementing Protein 5; X-ray Repair Cross-Complementing Protein 6; XRCC5 Protein; XRCC6 Protein
Related Numbers: EC 3.6.4.12
Public MeSH Note: 2017; KU AUTOANTIGEN was indexed under DNA-BINDING PROTEINS and ANTIGENS, NUCLEAR 2003-2016; and under ANTIGENS, SURFACE 1986-1991 and NUCLEAR PROTEINS 1985-2003
History Note: 2017 (1986)
Date Established: 2017/01/01
Date of Entry: 2016/07/08
Revision Date: 2017/05/24

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0138075
Related Numbers: EC 3.6.4.12
Scope Note: An ATP-dependent DNA HELICASE that preferentially binds SINGLE-STRANDED DNA. It is a heterodimer consisting of an 80 kDa subunit (XRCC5) and 70 kDa subunit (XRCC6) that functions with DNA LIGASE IV in the repair of DOUBLE-STRANDED DNA BREAKS and V(D)J RECOMBINATION.
Terms: Ku Autoantigen Preferred Term
Term UI T000898509
Date04/07/2016
LexicalTag NON
ThesaurusID NLM (1986); Ku Antigen
Term UI T000898510
Date04/07/2016
LexicalTag NON
ThesaurusID NLM (1986); G22P1 Antigen
Term UI T000898511
Date04/07/2016
LexicalTag ABX
ThesaurusID NLM (2004); Ku Heterodimer
Term UI T000898513
Date04/07/2016
LexicalTag NON
ThesaurusID NLM (2017); Ku Protein
Term UI T000898512
Date04/07/2016
LexicalTag NON
ThesaurusID NLM (2017)

Concept UI: M0453319
Terms: Ku70 Antigen Preferred Term
Term UI T000900461
Date05/06/2016
LexicalTag NON
ThesaurusID NLM (1995); XRCC6 Protein
Term UI T000900459
Date05/06/2016
LexicalTag ABX
ThesaurusID NLM (2017); X-ray Repair Cross-Complementing Protein 6
Term UI T000900460
Date05/06/2016
LexicalTag NON
ThesaurusID NLM (2017); Ku Autoantigen, 70 kDa
Term UI T000900462
Date05/06/2016
LexicalTag ABX
ThesaurusID NLM (2004)

Concept UI: M0466161
Terms: Ku80 Antigen Preferred Term
Term UI T000900463
Date05/06/2016
LexicalTag NON
ThesaurusID NLM (2005); XRCC5 Protein
Term UI T000900457
Date05/06/2016
LexicalTag ABX
ThesaurusID NLM (2017); X-ray Repair Cross-Complementing Protein 5
Term UI T000900458
Date05/06/2016
LexicalTag NON
ThesaurusID NLM (2017); Ku Autoantigen, 80 kDa
Term UI T000900464
Date05/06/2016
LexicalTag ABX
ThesaurusID NLM (2004)

Ku Autoantigen MeSH Descriptor Data 2024