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MutS Proteins MeSH Descriptor Data 2025


MeSH Heading
MutS Proteins
Tree Number(s)
D08.811.074.844
D08.811.277.040.025.292
D12.776.260.556
Unique ID
D000074080
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074080
Scope Note
DNA repair proteins that include the bacterial MutS DNA mismatch-binding protein and its eukaryotic homologs that function in DNA MISMATCH REPAIR and recombination of DNA during MEIOSIS. MutS has a conserved mismatch recognition domain characterized by GxFxE, or similar AMINO ACID MOTIFS that also occur in eukaryotic homologs such as MSH1, MSH6, and MSH8. All MutS proteins also contain a highly-conserved ATP-binding domain and most have weak ATPase activity.
Entry Term(s)
MutS Homolog
MutS Homolog Protein
MutS Homolog Proteins
MutS Homologs
MutS Protein
Registry Numbers
EC 3.6.1.3
0
Previous Indexing
Adenosine Triphosphatases (1997-2017)
DNA-Binding Proteins (1997-2017)
MutS DNA Mismatch-Binding Protein (2006-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2020/05/27
MutS Proteins Preferred
MutS Homolog Proteins Narrower
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