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MutS Proteins MeSH Descriptor Data 2022


MeSH Heading
MutS Proteins
Tree Number(s)
D08.811.074.844
D08.811.277.040.025.292
D12.776.260.556
Unique ID
D000074080
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000074080
Scope Note
DNA repair proteins that include the bacterial MutS DNA mismatch-binding protein and its eukaryotic homologs that function in DNA MISMATCH REPAIR and recombination of DNA during MEIOSIS. MutS has a conserved mismatch recognition domain characterized by GxFxE, or similar AMINO ACID MOTIFS that also occur in eukaryotic homologs such as MSH1, MSH6, and MSH8. All MutS proteins also contain a highly-conserved ATP-binding domain and most have weak ATPase activity.
Entry Term(s)
MutS Homolog
MutS Homolog Protein
MutS Homolog Proteins
MutS Homologs
MutS Protein
Registry Number
EC 3.6.1.3
Previous Indexing
Adenosine Triphosphatases (1997-2017)
DNA-Binding Proteins (1997-2017)
MutS DNA Mismatch-Binding Protein (2006-2017)
Public MeSH Note
2018
History Note
2018
Date Established
2018/01/01
Date of Entry
2017/07/11
Revision Date
2020/05/27
MutS Proteins Preferred
MutS Homolog Proteins Narrower
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