MeSH Browser

MeSH Heading: Proto-Oncogene Proteins c-sis
Tree Number(s): D12.644.276.910.650; D12.776.124.625.650; D12.776.260.690; D12.776.467.910.650; D12.776.624.664.700.195; D23.529.910.650
Unique ID: D020574
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020574
Scope Note: Cellular DNA-binding proteins encoded by the sis gene (GENES, SIS). c-sis proteins make up the B chain of PLATELET-DERIVED GROWTH FACTOR. Overexpression of c-sis causes tumorigenesis.
Entry Term(s): PDGFB; Platelet-Derived Growth Factor B; Proto-Oncogene Products c-sis; Proto-Oncogene Protein sis; Proto-Oncogene Proteins sis; c-sis Proteins; sis Proto-Oncogene Proteins
Previous Indexing: Platelet-Derived Growth Factor (1990-1999); Proto-Oncogene Proteins (1987-1999)
See Also: Genes, sis
Public MeSH Note: 2000; PROTO-ONCOGENE PROTEIN SIS was indexed under PROTO-ONCOGENE PROTEINS 1987-1999 & PLATELET-DERIVED GROWTH FACTOR 1990-1999
History Note: 2000; use PROTO-ONCOGENE PROTEINS C-SIS (NM) 1987-1999
Date Established: 2000/01/01
Date of Entry: 1999/11/03
Revision Date: 2006/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
  - Intercellular Signaling Peptides and Proteins [D12.644.276]
    - Platelet-Derived Growth Factor [D12.644.276.910]
      - Proto-Oncogene Proteins c-sis [D12.644.276.910.650]
        
        Becaplermin [D12.644.276.910.650.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Blood Proteins [D12.776.124]
    - Platelet-Derived Growth Factor [D12.776.124.625]
      - Proto-Oncogene Proteins c-sis [D12.776.124.625.650]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - DNA-Binding Proteins [D12.776.260]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intercellular Signaling Peptides and Proteins [D12.776.467]
    - Platelet-Derived Growth Factor [D12.776.467.910]
      - Proto-Oncogene Proteins c-sis [D12.776.467.910.650]
        
        Becaplermin [D12.776.467.910.650.500]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Neoplasm Proteins [D12.776.624]
    - Oncogene Proteins [D12.776.624.664]
      - Proto-Oncogene Proteins [D12.776.624.664.700]
        
        Axl Receptor Tyrosine Kinase [D12.776.624.664.700.013]
        
        Bcl-2-Like Protein 11 [D12.776.624.664.700.025]
        
        c-Mer Tyrosine Kinase [D12.776.624.664.700.037]
        
        Chemokine CXCL1 [D12.776.624.664.700.049]
        
        Cyclin D1 [D12.776.624.664.700.100]
        
        Fibroblast Growth Factor 4 [D12.776.624.664.700.110]
        
        Fibroblast Growth Factor 6 [D12.776.624.664.700.112]
        
        fms-Like Tyrosine Kinase 3 [D12.776.624.664.700.114]
        
        Janus Kinase 2 [D12.776.624.664.700.117]
        
        KRIT1 Protein [D12.776.624.664.700.119]
        
        Kruppel-Like Factor 6 [D12.776.624.664.700.120]
        
        Lipocalin-2 [D12.776.624.664.700.123]
        
        Lymphocyte Specific Protein Tyrosine Kinase p56(lck) [D12.776.624.664.700.128]
        
        MDS1 and EVI1 Complex Locus Protein [D12.776.624.664.700.129]
        
        MutS Homolog 2 Protein [D12.776.624.664.700.130]
        
        Myeloid-Lymphoid Leukemia Protein [D12.776.624.664.700.148]
        
        N-Myc Proto-Oncogene Protein [D12.776.624.664.700.158]
        
        Pre-B-Cell Leukemia Transcription Factor 1 [D12.776.624.664.700.163]
        
        B-Cell Lymphoma 3 Protein [D12.776.624.664.700.165]
        
        Proto-Oncogene Mas [D12.776.624.664.700.166]
        
        Proto-Oncogene Proteins c-abl [D12.776.624.664.700.167]
        
        Proto-Oncogene Proteins c-akt [D12.776.624.664.700.168]
        
        Proto-Oncogene Proteins c-bcl-2 [D12.776.624.664.700.169]
        
        Proto-Oncogene Proteins c-bcl-6 [D12.776.624.664.700.170]
        
        Proto-Oncogene Proteins c-bcr [D12.776.624.664.700.171]
        
        Proto-Oncogene Proteins c-cbl [D12.776.624.664.700.172]
        
        Proto-Oncogene Proteins c-crk [D12.776.624.664.700.174]
        
        Proto-Oncogene Proteins c-ets [D12.776.624.664.700.175]
        
        Proto-Oncogene Proteins c-fes [D12.776.624.664.700.177]
        
        Proto-Oncogene Proteins c-fos [D12.776.624.664.700.179]
        
        Proto-Oncogene Proteins c-fyn [D12.776.624.664.700.180]
        
        Proto-Oncogene Proteins c-hck [D12.776.624.664.700.181]
        
        Proto-Oncogene Proteins c-jun [D12.776.624.664.700.182]
        
        Proto-Oncogene Proteins c-kit [D12.776.624.664.700.183]
        
        Proto-Oncogene Proteins c-maf [D12.776.624.664.700.184]
        
        Proto-Oncogene Proteins c-mdm2 [D12.776.624.664.700.185]
        
        Proto-Oncogene Proteins c-met [D12.776.624.664.700.186]
        
        Proto-Oncogene Proteins c-mos [D12.776.624.664.700.187]
        
        Proto-Oncogene Proteins c-myb [D12.776.624.664.700.188]
        
        Proto-Oncogene Proteins c-myc [D12.776.624.664.700.189]
        
        Proto-Oncogene Proteins c-pim-1 [D12.776.624.664.700.191]
        
        Proto-Oncogene Proteins c-rel [D12.776.624.664.700.192]
        
        Proto-Oncogene Proteins c-ret [D12.776.624.664.700.194]
        
        Proto-Oncogene Proteins c-sis [D12.776.624.664.700.195]
        
        Proto-Oncogene Proteins c-vav [D12.776.624.664.700.198]
        
        Proto-Oncogene Proteins c-yes [D12.776.624.664.700.199]
        
        Proto-Oncogene Proteins p21(ras) [D12.776.624.664.700.200]
        
        Proto-Oncogene Proteins pp60(c-src) [D12.776.624.664.700.202]
        
        raf Kinases [D12.776.624.664.700.204]
        
        Receptor, ErbB-2 [D12.776.624.664.700.642]
        
        Receptor, ErbB-3 [D12.776.624.664.700.790]
        
        Receptor, ErbB-4 [D12.776.624.664.700.791]
        
        Receptor, Fibroblast Growth Factor, Type 3 [D12.776.624.664.700.792]
        
        Receptor, Macrophage Colony-Stimulating Factor [D12.776.624.664.700.800]
        
        Receptor, Notch4 [D12.776.624.664.700.815]
        
        Receptors, Thyroid Hormone [D12.776.624.664.700.830]
        
        RNA-Binding Protein EWS [D12.776.624.664.700.913]
        
        RNA-Binding Protein FUS [D12.776.624.664.700.915]
        
        RUNX1 Translocation Partner 1 Protein [D12.776.624.664.700.936]
        
        Stathmin [D12.776.624.664.700.957]
        
        T-Cell Acute Lymphocytic Leukemia Protein 1 [D12.776.624.664.700.960]
        
        Wnt-5a Protein [D12.776.624.664.700.962]
        
        Wnt1 Protein [D12.776.624.664.700.967]
        
        Wnt2 Protein [D12.776.624.664.700.978]
        
        Zinc Finger Protein GLI1 [D12.776.624.664.700.989]

Biological Factors [D23]
- Intercellular Signaling Peptides and Proteins [D23.529]
  - Platelet-Derived Growth Factor [D23.529.910]
    - Proto-Oncogene Proteins c-sis [D23.529.910.650]
      - Becaplermin [D23.529.910.650.500]

Proto-Oncogene Proteins c-sis Preferred

Concept UI: M0328562
Scope Note: Cellular DNA-binding proteins encoded by the sis gene (GENES, SIS). c-sis proteins make up the B chain of PLATELET-DERIVED GROWTH FACTOR. Overexpression of c-sis causes tumorigenesis.
Terms: Proto-Oncogene Proteins c-sis Preferred Term
Term UI T358562
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); PDGFB
Term UI T173640
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Platelet-Derived Growth Factor B
Term UI T361950
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Proto-Oncogene Products c-sis
Term UI T361947
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); c-sis Proteins
Term UI T361945
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Proto-Oncogene Proteins sis
Term UI T361948
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); sis Proto-Oncogene Proteins
Term UI T361946
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Proto-Oncogene Protein sis
Term UI T173645
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000)

Proto-Oncogene Proteins c-sis MeSH Descriptor Data 2024