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Proto-Oncogene Proteins c-bcl-2 MeSH Descriptor Data 2025
Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma.
Entry Term(s)
B-Cell Leukemia 2 Family Proteins
BCL2 Family Proteins
BCL2 Proteins
bcl-2 Proto-Oncogene Proteins
c-bcl-2 Proteins
Registry Numbers
0
Previous Indexing
Proto-Oncogene Proteins (1989-1996)
Public MeSH Note
97; PROTO-ONCOGENE PROTEIN BCL-2 was indexed under PROTO-ONCOGENE PROTEINS 1989-96
Online Note
use PROTO-ONCOGENE PROTEINS C-BCL-2 (NM) to search PROTO-ONCOGENE PROTEIN BCL-2 1989-96
Membrane proteins encoded by the BCL-2 GENES and serving as potent inhibitors of cell death by APOPTOSIS. The proteins are found on mitochondrial, microsomal, and NUCLEAR MEMBRANE sites within many cell types. Overexpression of bcl-2 proteins, due to a translocation of the gene, is associated with follicular lymphoma.