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Proto-Oncogene Proteins c-akt MeSH Descriptor Data 2022


MeSH Heading
Proto-Oncogene Proteins c-akt
Tree Number(s)
D08.811.913.696.620.682.700.755
D12.776.476.563.755
D12.776.624.664.700.168
Unique ID
D051057
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051057
Scope Note
Protein-serine-threonine kinases that contain PLECKSTRIN HOMOLOGY DOMAINS and are activated by PHOSPHORYLATION in response to GROWTH FACTORS or INSULIN. They play a major role in cell metabolism, growth, and survival as a core component of SIGNAL TRANSDUCTION. Three isoforms have been described in mammalian cells.
Entry Term(s)
AKT1 Protein Kinase
AKT2 Protein Kinase
AKT3 Protein Kinase
Akt-alpha Protein
Akt-beta Protein
Akt-gamma Protein
Protein Kinase B
Protein Kinase B alpha
Protein Kinase B beta
Protein Kinase B gamma
Protein-Serine-Threonine Kinase (Rac)
Proto-Oncogene Protein Akt
Proto-Oncogene Protein RAC
Proto-Oncogene Proteins c-akt1
Proto-Oncogene Proteins c-akt2
Proto-Oncogene Proteins c-akt3
RAC-PK Protein
Rac Protein Kinase
Rac-PK alpha Protein
Rac-PK beta Protein
Related to A and C-Protein
akt Proto-Oncogene Protein
c-akt Protein
c-akt Proto-Oncogene Protein
Registry Number
EC 2.7.11.1
Related Numbers
EC 2.7.11.1
Public MeSH Note
2006; PROTO-ONCOGENE PROTEINS C-AKT was indexed under PROTEIN-SERINE-THREONINE KINASES & PROTO-ONCOGENE PROTEINS 1987-2005
History Note
2006(1987)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2021/05/21
Proto-Oncogene Proteins c-akt Preferred
Proto-Oncogene Proteins c-akt1 Narrower
Proto-Oncogene Proteins c-akt2 Narrower
Proto-Oncogene Proteins c-akt3 Narrower
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