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Cyclin D1 MeSH Descriptor Data 2025


MeSH Heading
Cyclin D1
Tree Number(s)
D12.644.360.262.150.100
D12.776.167.218.150.100
D12.776.476.262.150.100
D12.776.624.664.700.100
Unique ID
D019938
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D019938
Scope Note
Protein encoded by the bcl-1 gene which plays a critical role in regulating the cell cycle. Overexpression of cyclin D1 is the result of bcl-1 rearrangement, a t(11;14) translocation, and is implicated in various neoplasms.
Entry Term(s)
CCND1 Protein
PRAD1 Protein
Proto-Oncogene Products bcl-1
Proto-Oncogene Protein bcl-1
Proto-Oncogene Proteins c-bcl-1
bcl-1 Proto-Oncogene Products
bcl-1 Proto-Oncogene Proteins
bcl1 Proto-Oncogene Proteins
c-bcl-1 Proteins
Registry Numbers
136601-57-5
Previous Indexing
Cyclins (1991-1997)
Oncogene Proteins (1991-1997)
Proto-Oncogene Proteins (1990-1997)
See Also
Lymphoma, Mantle-Cell
Public MeSH Note
98; PRAD1 PROTEIN (now CYCLIN D1) was indexed under CYCLINS & ONCOGENE PROTEINS 1991-97; PROTO-ONCOGENE PROTEIN BCL-1 (now CYCLIN D1) was indexed under PROTO-ONCOGENE PROTEINS 1990-97
History Note
98; use CYCLIN D1 (NM) 1990-97
Date Established
1998/01/01
Date of Entry
1997/06/20
Revision Date
2015/11/23
Cyclin D1 Preferred
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