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Janus Kinase 2 MeSH Descriptor Data 2022


MeSH Heading
Janus Kinase 2
Tree Number(s)
D08.811.913.696.620.682.725.124.200
D12.776.476.568.124.200
D12.776.624.664.700.117
Unique ID
D053614
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053614
Scope Note
A Janus kinase subtype that is involved in signaling from GROWTH HORMONE RECEPTORS; PROLACTIN RECEPTORS; and a variety of CYTOKINE RECEPTORS such as ERYTHROPOIETIN RECEPTORS and INTERLEUKIN RECEPTORS. Dysregulation of Janus kinase 2 due to GENETIC TRANSLOCATIONS have been associated with a variety of MYELOPROLIFERATIVE DISORDERS.
Entry Term(s)
JAK-2 Protein Tyrosine Kinase
JAK2 Protein Tyrosine Kinase
Registry Number
EC 2.7.10.2
See Also
src Homology Domains
Public MeSH Note
2007; JANUS KINASE 2 was indexed under PROTEIN-TYROSINE KINASE & PROTO-ONCOGENE PROTEINS 1992-2006
History Note
2007(1992)
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2021/05/21
Janus Kinase 2 Preferred
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