- Concept UI
- M0087111
- Registry Numbers
- 0
- Scope Note
- A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.
- Terms
-
RNA-Binding Protein FUS
Preferred Term
Term UI
T471624
Date11/30/2001
LexicalTag
ACX
ThesaurusID
NLM (2003)
-
TLS Protein
Term UI
T117103
Date01/01/1955
LexicalTag
ACX
ThesaurusID
NLM (2003)
-
hnRNP P2
Term UI
T117114
Date01/01/1955
LexicalTag
ACX
ThesaurusID
NLM (2003)
-
Translocated in Liposarcoma Protein
Term UI
T471625
Date11/30/2001
LexicalTag
NON
ThesaurusID
NLM (2003)
-
FUS RNA-Binding Protein
Term UI
T471636
Date11/30/2001
LexicalTag
ACX
ThesaurusID
NLM (2003)
-
Fusion Protein in Myxoid Liposarcoma
Term UI
T471637
Date11/30/2001
LexicalTag
NON
ThesaurusID
NLM (2003)
-
FUS Protein
Term UI
T117095
Date01/01/1955
LexicalTag
ACX
ThesaurusID
NLM (2003)
-
POMp75 Protein
Term UI
T471638
Date11/30/2001
LexicalTag
ACX
ThesaurusID
NLM (2003)