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Heterogeneous-Nuclear Ribonucleoprotein K MeSH Descriptor Data 2022


MeSH Heading
Heterogeneous-Nuclear Ribonucleoprotein K
Tree Number(s)
D12.776.157.725.813.750.500
D12.776.260.268
D12.776.664.962.813.750.500
Unique ID
D034641
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D034641
Annotation
see SCR for specific hnRNP entries
Scope Note
A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.
Entry Term(s)
Heterogeneous Nuclear Ribonucleoprotein Particle K Protein
dC-Stretch-Binding Protein
hnRNP K
hnRNP K Protein
Registry Number
0
Previous Indexing
DNA-Binding Proteins (1994-2002)
Ribonucleoproteins (1994-2002)
Public MeSH Note
2003; DC-STRETCH-BINDING PROTEIN (now HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K) was indexed under DNA-BINDING PROTEINS 1994-2002; HNRNP K was indexed under RIBONUCLEOPROTEINS 1994-2002
History Note
2003; use HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K (NM) 1994-2002; for HNRNP K use HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS (NM) 1994-2002
Date Established
2003/01/01
Date of Entry
2002/07/03
Revision Date
2015/04/15
Heterogeneous-Nuclear Ribonucleoprotein K Preferred
hnRNP K Protein Narrower
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