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Heterogeneous-Nuclear Ribonucleoprotein K MeSH Descriptor Data 2025
A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.
Entry Term(s)
Heterogeneous Nuclear Ribonucleoprotein Particle K Protein
dC-Stretch-Binding Protein
hnRNP K
hnRNP K Protein
Registry Numbers
0
Previous Indexing
DNA-Binding Proteins (1994-2002)
Ribonucleoproteins (1994-2002)
Public MeSH Note
2003; DC-STRETCH-BINDING PROTEIN (now HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K) was indexed under DNA-BINDING PROTEINS 1994-2002; HNRNP K was indexed under RIBONUCLEOPROTEINS 1994-2002
History Note
2003; use HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN K (NM) 1994-2002; for HNRNP K use HETEROGENEOUS-NUCLEAR RIBONUCLEOPROTEINS (NM) 1994-2002
A heterogeneous-nuclear ribonucleoprotein found in the CELL NUCLEUS and the CYTOPLASM. Heterogeneous-nuclear ribonucleoprotein K has been implicated in the regulation of gene expression at nearly all levels: GENETIC TRANSCRIPTION; mRNA processing (RNA PROCESSING, POST-TRANSCRIPTIONAL), mRNA transport, mRNA stability, and translation (TRANSLATION, GENETIC). The hnRNP protein has a strong affinity for polypyrimidine-rich RNA and for single-stranded polypyrimidine-rich DNA. Multiple hnRNP K protein isoforms exist due to alternative splicing and display different nucleic-acid-binding properties.