MeSH Browser

MeSH Heading: NF-kappa B
Tree Number(s): D05.500.672; D12.776.260.600; D12.776.660.600; D12.776.930.600
Unique ID: D016328
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D016328
Scope Note: Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
Entry Version: NFKB
Entry Term(s): Ig-EBP-1; Immunoglobulin Enhancer-Binding Protein; NF-kB; NF-kappa B Complex; NF-kappaB; Nuclear Factor kappa B; Nuclear Factor-Kappab; Transcription Factor NF-kB; kappa B Enhancer Binding Protein
Previous Indexing: DNA-Binding Proteins (1987-1990); Transcription Factors (1987-1990)
See Also: I-kappa B Proteins
Public MeSH Note: 91
History Note: 91
Date Established: 1991/01/01
Date of Entry: 1990/06/19
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0024955
Scope Note: Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.
Terms: NF-kappa B Preferred Term
Term UI T048719
Date01/01/1999
LexicalTag ACR
ThesaurusID NLM (1991); Immunoglobulin Enhancer-Binding Protein
Term UI T048717
Date04/19/1990
LexicalTag NON
ThesaurusID NLM (1991); kappa B Enhancer Binding Protein
Term UI T048718
Date05/14/1990
LexicalTag NON
ThesaurusID NLM (1991); Nuclear Factor kappa B
Term UI T048720
Date05/01/1990
LexicalTag NON
ThesaurusID NLM (1991); Transcription Factor NF-kB
Term UI T048721
Date05/14/1990
LexicalTag NON
ThesaurusID NLM (1991); NF-kappaB
Term UI T558119
Date11/13/2003
LexicalTag NON
ThesaurusID NLM (2005); NF-kB
Term UI T048722
Date04/19/1990
LexicalTag NON
ThesaurusID NLM (1991); Nuclear Factor-Kappab
Term UI T000941537
Date03/26/2018
LexicalTag NON
ThesaurusID NLM (2019)

NF-kappa B MeSH Descriptor Data 2024