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Ataxins MeSH Descriptor Data 2022


MeSH Heading
Ataxins
Tree Number(s)
D12.776.631.069
D12.776.660.075
Unique ID
D000067528
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000067528
Scope Note
A family of predominantly nuclear proteins that regulate gene transcription and protein degradation. The expansion of CAG trinucleotide repeats in genes that encode Ataxins is associated with SPINOCEREBELLAR ATAXIAS (SCA). In SCA patients, the number of CAG repeats correlates with the severity of disease and inversely correlates with the age of disease onset.
Entry Term(s)
Ataxin
Ataxin Protein
Ataxin Proteins
Spinocerebellar Ataxia Protein
Spinocerebellar Ataxia Proteins
Registry Number
0
Previous Indexing
Nerve Tissue Proteins (1995-2015)
Nuclear Proteins (1995-2015)
See Also
Spinocerebellar Ataxias
Public MeSH Note
2016
History Note
2016
Date Established
2016/01/01
Date of Entry
2015/07/06
Revision Date
2020/05/27
Ataxins Preferred
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