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A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.
Entry Term(s)
B-50 Protein
GAP-43
GAP43 Protein
Growth-Associated Protein 43
Nerve Growth Cone Membrane Protein GAP-43
Neuromodulin
Phosphoprotein B-50
Phosphoprotein F1
Phosphoprotein pp46
Registry Numbers
0
Previous Indexing
Calmodulin-Binding Proteins (1986-1992)
Membrane Glycoproteins (1988-1997)
Membrane Proteins (1986-1989)
Nerve Tissue Proteins (1986-1997)
Public MeSH Note
98; NERVE GROWTH CONE MEMBRANE PROTEIN GAP-43 (now GAP-43 PROTEIN) was indexed under NERVE TISSUE PROTEINS 1986-97, MEMBRANE GLYCOPROTEINS 1988-97, CALMODULIN-BINDING PROTEINS 1986-92, & MEMBRANE PROTEINS 1986-89.
A nervous tissue specific protein which is highly expressed in NEURONS during development and NERVE REGENERATION. It has been implicated in neurite outgrowth, long-term potentiation, SIGNAL TRANSDUCTION, and NEUROTRANSMITTER release. (From Neurotoxicology 1994;15(1):41-7) It is also a substrate of PROTEIN KINASE C.