NLM Logo

Signaling Lymphocytic Activation Molecule Family MeSH Descriptor Data 2022


MeSH Heading
Signaling Lymphocytic Activation Molecule Family
Tree Number(s)
D12.776.395.550.736
D12.776.543.550.746
D12.776.543.750.705.970
Unique ID
D000071176
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000071176
Scope Note
Type-I membrane glycoproteins that are expressed primarily on the surface of CD4 or CD8-positive T-CELLS; NATURAL KILLER CELLS; and some populations of B CELLS. They are characterized by an N-terminal, extracellular IMMUNOGLOBULIN-LIKE DOMAIN and a membrane-proximal IMMUNOGLOBULIN C2-SET DOMAIN. SLAMF receptors typically signal through homophilic interactions and are important for mediating the immune response and immune cell differentiation.
Entry Term(s)
SLAM Family Receptors
SLAMF Receptors
Signaling Lymphocytic Activation Molecule Family Receptors
Signaling Lymphocytic Activation Molecule Receptors
Signaling Lymphocytic Activation Molecules
Registry Number
0
Previous Indexing
Antigens, CD (1997-2016)
Receptors, Cell Surface (1997-2016)
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2017/05/24
Signaling Lymphocytic Activation Molecule Family Preferred
page delivered in 0.214s