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PHEX Phosphate Regulating Neutral Endopeptidase MeSH Descriptor Data 2024


MeSH Heading
PHEX Phosphate Regulating Neutral Endopeptidase
Tree Number(s)
D08.811.277.656.300.480.616
D08.811.277.656.675.374.616
D09.400.430.890.611
D12.776.395.550.611
D12.776.543.550.607
Unique ID
D053402
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053402
Scope Note
A membrane-bound metalloendopeptidase that may play a role in the degradation or activation of a variety of PEPTIDE HORMONES and INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS. Genetic mutations that result in loss of function of this protein are a cause of HYPOPHOSPHATEMIC RICKETS, X-LINKED DOMINANT.
Entry Term(s)
PEX Phosphate Regulating Neutral Endopeptidase
Phosphate Regulating Endopeptidase Homolog, X-Linked
Phosphate Regulating Neutral Endopeptidase
X-Linked Phosphate Regulating Endopeptidase Homolog
Registry Number
EC 3.4.24.-
Public MeSH Note
2007; PHEX PHOSPHATE REGULATING NEUTRAL ENDOPEPTIDASE was indexed under MEMBRANE GLYCOPROTEINS & METALLOENDOPEPTIDASES 2006, & PROTEINS 1995-2006
History Note
2007(1995)
Entry Combination
deficiency:Familial Hypophosphatemic Rickets
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2023/03/16
PHEX Phosphate Regulating Neutral Endopeptidase Preferred
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