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Procollagen N-Endopeptidase MeSH Descriptor Data 2023


MeSH Heading
Procollagen N-Endopeptidase
Tree Number(s)
D08.811.277.656.300.480.664
D08.811.277.656.675.374.664
Unique ID
D011348
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D011348
Scope Note
An extracellular endopeptidase which excises a block of peptides at the amino terminal, nonhelical region of the procollagen molecule with the formation of collagen. Absence or deficiency of the enzyme causes accumulation of procollagen which results in the inherited connective tissue disorder--dermatosparaxis. EC 3.4.24.14.
Entry Term(s)
Procollagen N-Proteinase
Procollagen Peptidase
Registry Number
EC 3.4.24.14
Previous Indexing
Collagen (1966-1976)
Peptide Peptidohydrolases (1966-1976)
Protein Precursors (1973-1976)
Public MeSH Note
97; was PROCOLLAGEN PEPTIDASE 1977-96 (see under PEPTIDE PEPTIDOHYDROLASES 1977-90)
History Note
97; was PROCOLLAGEN PEPTIDASE 1977-96 (see under ENDOPEPTIDASES 1977-90)
Date Established
1991/01/01
Date of Entry
1976/04/27
Revision Date
2003/07/09
Procollagen N-Endopeptidase Preferred
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