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Immunoglobulin Domains MeSH Descriptor Data 2022


MeSH Heading
Immunoglobulin Domains
Tree Number(s)
G02.111.570.820.709.275.750.250
Unique ID
D000070557
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000070557
Scope Note
Compact globular protein domains of about 80 to 110 amino acids.They are characterized by two antiparallel beta sheets stabilized by HYDROPHOBIC INTERACTIONS and disulfide bonds between opposing strands. Three major subtypes of Ig domains are recognized: variable (V), intermediate (I), and constant (C1 or C2). Members of the immunoglobulin superfamily include ANTIGEN RECEPTORS; CYTOKINE RECEPTORS; and CELL ADHESION MOLECULES which possess immunoglobulin domains.
Entry Term(s)
Ig C2-set Domain
Ig Domain
Ig Domains
Ig Fold
Ig V-set Domain
Ig-like Domain
Immunoglobulin C1-set Domain
Immunoglobulin C2-set Domain
Immunoglobulin Domain
Immunoglobulin I-set Domain
Immunoglobulin V-set Domain
Immunoglobulin-like Domain
Previous Indexing
Immunoglobulins (1976-2016)
See Also
Immunoglobulin Constant Regions
Immunoglobulin Variable Region
Public MeSH Note
2017
History Note
2017
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2016/05/09
Immunoglobulin Domains Preferred
Immunoglobulin C1-set Domain Narrower
Immunoglobulin C2-set Domain Narrower
Immunoglobulin I-set Domain Narrower
Immunoglobulin-like Domain Related
Immunoglobulin V-set Domain Narrower
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