MeSH Browser

MeSH Heading: Receptor Protein-Tyrosine Kinases
Tree Number(s): D08.811.913.696.620.682.725.400; D12.776.476.568.400; D12.776.543.750.630
Unique ID: D020794
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D020794
Scope Note: A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity.
Entry Version: RPTK
Entry Term(s): PTK Receptor; PTK Receptors; Protein-Tyrosine Kinase Receptor; Receptor Protein-Tyrosine Kinase; Receptors, Protein-Tyrosine Kinase; Tyrosine Kinase Linked Receptor; Tyrosine Kinase Linked Receptors; Tyrosine Kinase Receptor; Tyrosine Kinase Receptors
Registry Numbers: EC 2.7.10.1
Previous Indexing: Protein-Tyrosine Kinase (1983-1993); Receptor Protein-Tyrosine Kinase (1994-1999); specific receptors (1983-1993)
Public MeSH Note: 2000; for RECEPTOR PROTEIN-TYROSINE KINASE see RECEPTOR PROTEIN-TYROSINE KINASE 1994-1999
History Note: 2000
Date Established: 2000/01/01
Date of Entry: 1999/11/05
Revision Date: 2021/05/21

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Transferases [D08.811.913]
    - Phosphotransferases [D08.811.913.696]
      - Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
        
        Protein Kinases [D08.811.913.696.620.682]
        
        Protein-Tyrosine Kinases [D08.811.913.696.620.682.725]
        
        Agammaglobulinaemia Tyrosine Kinase [D08.811.913.696.620.682.725.025]
        
        Dyrk Kinases [D08.811.913.696.620.682.725.037]
        
        Focal Adhesion Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.049]
        
        Janus Kinases [D08.811.913.696.620.682.725.124]
        
        Mitogen-Activated Protein Kinase Kinases [D08.811.913.696.620.682.725.200]
        
        Proto-Oncogene Proteins c-fes [D08.811.913.696.620.682.725.300]
        
        Receptor Protein-Tyrosine Kinases [D08.811.913.696.620.682.725.400]
        
        Anaplastic Lymphoma Kinase [D08.811.913.696.620.682.725.400.002]
        
        c-Mer Tyrosine Kinase [D08.811.913.696.620.682.725.400.003]
        
        Discoidin Domain Receptors [D08.811.913.696.620.682.725.400.005]
        
        ErbB Receptors [D08.811.913.696.620.682.725.400.009]
        
        fms-Like Tyrosine Kinase 3 [D08.811.913.696.620.682.725.400.020]
        
        Proto-Oncogene Proteins c-kit [D08.811.913.696.620.682.725.400.050]
        
        Proto-Oncogene Proteins c-met [D08.811.913.696.620.682.725.400.075]
        
        Proto-Oncogene Proteins c-ret [D08.811.913.696.620.682.725.400.087]
        
        Receptor Tyrosine Kinase-like Orphan Receptors [D08.811.913.696.620.682.725.400.093]
        
        Receptor, Fibroblast Growth Factor, Type 1 [D08.811.913.696.620.682.725.400.177]
        
        Receptor, Fibroblast Growth Factor, Type 2 [D08.811.913.696.620.682.725.400.178]
        
        Receptor, Fibroblast Growth Factor, Type 3 [D08.811.913.696.620.682.725.400.179]
        
        Receptor, Fibroblast Growth Factor, Type 4 [D08.811.913.696.620.682.725.400.180]
        
        Receptor, IGF Type 1 [D08.811.913.696.620.682.725.400.185]
        
        Receptor, Insulin [D08.811.913.696.620.682.725.400.200]
        
        Receptor, Macrophage Colony-Stimulating Factor [D08.811.913.696.620.682.725.400.500]
        
        Receptor, trkA [D08.811.913.696.620.682.725.400.660]
        
        Receptor, trkB [D08.811.913.696.620.682.725.400.700]
        
        Receptor, trkC [D08.811.913.696.620.682.725.400.800]
        
        Receptors, Eph Family [D08.811.913.696.620.682.725.400.850]
        
        Receptors, Platelet-Derived Growth Factor [D08.811.913.696.620.682.725.400.900]
        
        Receptors, TIE [D08.811.913.696.620.682.725.400.925]
        
        Receptors, Vascular Endothelial Growth Factor [D08.811.913.696.620.682.725.400.950]
        
        Axl Receptor Tyrosine Kinase [D08.811.913.696.620.682.725.400.975]
        
        Proto-Oncogene Proteins c-abl [D08.811.913.696.620.682.725.500]
        
        Syk Kinase [D08.811.913.696.620.682.725.650]
        
        src-Family Kinases [D08.811.913.696.620.682.725.800]
        
        ZAP-70 Protein-Tyrosine Kinase [D08.811.913.696.620.682.725.900]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Intracellular Signaling Peptides and Proteins [D12.776.476]
    - Protein-Tyrosine Kinases [D12.776.476.568]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Receptors, Cell Surface [D12.776.543.750]

Receptor Protein-Tyrosine Kinases Preferred

Concept UI: M0328256
Registry Numbers: EC 2.7.10.1
Scope Note: A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity.
Terms: Receptor Protein-Tyrosine Kinases Preferred Term
Term UI T358256
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); PTK Receptor
Term UI T000997100
Date11/18/2019
LexicalTag NON
ThesaurusID NLM (2021); Tyrosine Kinase Linked Receptor
Term UI T000997101
Date11/18/2019
LexicalTag NON
ThesaurusID NLM (2021); Receptor Protein-Tyrosine Kinase
Term UI T053448
Date01/01/1999
LexicalTag NON
ThesaurusID NLM (1994); Receptors, Protein-Tyrosine Kinase
Term UI T362041
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Tyrosine Kinase Linked Receptors
Term UI T362042
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Tyrosine Kinase Receptors
Term UI T362043
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Protein-Tyrosine Kinase Receptor
Term UI T362044
Date10/12/1999
LexicalTag NON
ThesaurusID NLM (2000); Tyrosine Kinase Receptor
Term UI T000997098
Date11/18/2019
LexicalTag NON
ThesaurusID NLM (2021); PTK Receptors
Term UI T362045
Date10/12/1999
LexicalTag ACX
ThesaurusID NLM (2000)

Receptor Protein-Tyrosine Kinases MeSH Descriptor Data 2025