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Receptor, Fibroblast Growth Factor, Type 2 MeSH Descriptor Data 2022


MeSH Heading
Receptor, Fibroblast Growth Factor, Type 2
Tree Number(s)
D08.811.913.696.620.682.725.400.178
D12.776.476.568.400.178
D12.776.543.750.630.441
D12.776.543.750.750.400.370.750
Unique ID
D051497
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D051497
Scope Note
A fibroblast growth factor receptor which contains three extracellular IMMUNOGLOBULIN I-SET DOMAINS and is expressed as two isoforms. One receptor isoform is expressed in the MESENCHYME and is activated by FIBROBLAST GROWTH FACTOR 2. A second isoform is expressed mainly by EPITHELIAL CELLS and is activated by FIBROBLAST GROWTH FACTOR 7 and FIBROBLAST GROWTH FACTOR 10. Mutation of the gene for fibroblast growth factor receptor 2 can result in craniosynostotic syndromes (e.g., APERT SYNDROME; and CROUZON SYNDROME).
Entry Term(s)
BEK Fibroblast Growth Factor Receptor
BEK Fibroblast Growth Factor Receptor Kinase
BEK Protein Tyrosine Kinase
Bek Fgf Receptor Kinase
Bek-Related Fibroblast Growth Factor-Receptor-1
CD332 Antigen
FGFR2 Protein
FGFR2b
FGFR2c
Fibroblast Growth Factor Receptor 2
Fibroblast Growth Factor Receptor 2b
Fibroblast Growth Factor Receptor 2c
Fibroblast Growth Factor Receptors 2
Fibroblast Growth Factor Receptors 2b
Receptor, Fibroblast Growth Factor 2b
Receptor, Fibroblast Growth Factor 2c
Registry Number
EC 2.7.10.1
Related Numbers
EC 2.7.10.1
See Also
Acrocephalosyndactylia
Antley-Bixler Syndrome Phenotype
Craniofacial Dysostosis
Public MeSH Note
2006; FIBROBLAST GROWTH FACTOR RECEPTOR 2 was indexed under RECEPTORS, FIBROBLAST GROWTH FACTOR & RECEPTOR PROTEIN-TYROSINE KINASE 2004-2005, & under PROTEIN-TYROSINE KINASE 1999-2003
History Note
2006(1999)
Date Established
2006/01/01
Date of Entry
2005/06/30
Revision Date
2021/05/21
Receptor, Fibroblast Growth Factor, Type 2 Preferred
Fibroblast Growth Factor Receptor 2c Narrower
Fibroblast Growth Factor Receptor 2b Narrower
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