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Agammaglobulinaemia Tyrosine Kinase MeSH Descriptor Data 2022


MeSH Heading
Agammaglobulinaemia Tyrosine Kinase
Tree Number(s)
D08.811.913.696.620.682.725.025
D12.776.476.568.025
Unique ID
D000077329
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000077329
Scope Note
A non-receptor tyrosine kinase that is essential for the development, maturation, and signaling of B-LYMPHOCYTES. It contains an N-terminal zinc finger motif and localizes primarily to the PLASMA MEMBRANE and nucleus of B-lymphocytes. Mutations in the gene that encode this kinase are associated with X-LINKED AGAMMAGLOBULINEMIA.
Entry Term(s)
B Cell Progenitor Kinase
Bruton's Tyrosine Kinase
Registry Number
EC 2.7.10.2
Public MeSH Note
2019; AGAMMAGLOBULINAEMIA TYROSINE KINASE was indexed under PROTEIN-TYROSINE KINASES 1993-2018
History Note
2019 (1993)
Date Established
2019/01/01
Date of Entry
2018/07/09
Revision Date
2021/05/20
Agammaglobulinaemia Tyrosine Kinase Preferred
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