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Syk Kinase MeSH Descriptor Data 2022


MeSH Heading
Syk Kinase
Tree Number(s)
D08.811.913.696.620.682.725.650
D12.776.476.568.650
Unique ID
D000072377
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D000072377
Scope Note
An SH2 domain-containing non-receptor tyrosine kinase that regulates signal transduction downstream of a variety of receptors including B-CELL ANTIGEN RECEPTORS. It functions in both INNATE IMMUNITY and ADAPTIVE IMMUNITY and also mediates signaling in CELL ADHESION; OSTEOGENESIS; PLATELET ACTIVATION; and vascular development.
Entry Term(s)
SYK Tyrosine Kinase
Spleen Tyrosine Kinase
Registry Number
EC 2.7.10.2
See Also
src Homology Domains
Public MeSH Note
2017; SYK KINASE was indexed under PROTEIN-TYROSINE KINASES and INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS 2006-2016; and under ENZYME PRECURSORS 1992-2006
History Note
2017 (1992)
Date Established
2017/01/01
Date of Entry
2016/07/08
Revision Date
2021/06/28
Syk Kinase Preferred
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