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Janus Kinases MeSH Descriptor Data 2022


MeSH Heading
Janus Kinases
Tree Number(s)
D08.811.913.696.620.682.725.124
D12.776.476.568.124
Unique ID
D053612
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053612
Scope Note
A family of intracellular tyrosine kinases that participate in the signaling cascade of cytokines by associating with specific CYTOKINE RECEPTORS. They act upon STAT TRANSCRIPTION FACTORS in signaling pathway referred to as the JAK/STAT pathway. The name Janus kinase refers to the fact the proteins have two phosphate-transferring domains.
Entry Term(s)
JAK Kinases
Janus Kinase
Registry Number
EC 2.7.10.2
See Also
src Homology Domains
Public MeSH Note
2007
History Note
2007
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2021/05/21
Janus Kinases Preferred
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