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Costimulatory and Inhibitory T-Cell Receptors MeSH Descriptor Data 2022


MeSH Heading
Costimulatory and Inhibitory T-Cell Receptors
Tree Number(s)
D12.776.543.750.705.222
Unique ID
D061025
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D061025
Scope Note
A family of receptors that modulate the activation of T-LYMPHOCYTES by the T-CELL ANTIGEN RECEPTOR. The receptors are responsive to one or more B7 ANTIGENS found on ANTIGEN-PRESENTING CELLS and, depending upon the specific ligand-receptor combination, modulate a variety of T-cell functions such as the rate of clonal expansion, CELL SURVIVAL and cytokine production. Although commonly referred to as costimulatory receptors, some of the receptors have inhibitory effects such as inducing PERIPHERAL TOLERANCE.
Entry Term(s)
Costimulatory T-Cell Receptors
Costimulatory T-Lymphocyte Receptors
Costimulatory and Inhibitory T-Lymphocyte Receptors
Inhibitory T-Cell Receptors
Inhibitory T-Lymphocyte Receptors
Receptors, Costimulatory and Inhibitory, T-Lymphocyte
Receptors, Costimulatory, T-Lymphocyte
Receptors, Inhibitory, T-Cell
Registry Number
0
Public MeSH Note
2012
History Note
2012
Date Established
2012/01/01
Date of Entry
2011/06/24
Costimulatory and Inhibitory T-Cell Receptors Preferred
Costimulatory T-Cell Receptors Narrower
Inhibitory T-Cell Receptors Narrower
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