MeSH Browser

MeSH Heading: Programmed Cell Death 1 Receptor
Tree Number(s): D12.776.465.844; D12.776.543.750.705.222.875; D23.050.301.264.894.790; D23.101.100.894.790
Unique ID: D061026
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D061026
Scope Note: An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.
Entry Term(s): Antigens, CD279; CD279 Antigen; PD-1 Protein; PD-1 Receptor; PD1 Receptor; Programmed Cell Death 1 Protein; Programmed Cell Death Protein 1
Previous Indexing: Antigens, CD (1997-2011); Antigens, Surface (1997-2006); Apoptosis Regulatory Proteins (1977-2011)
See Also: Immunoglobulin Domains
Public MeSH Note: 2012
History Note: 2012
Date Established: 2012/01/01
Date of Entry: 2011/06/24
Revision Date: 2020/03/27

Allowable Qualifiers: administration & dosage (AD)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

physiology (PH)

radiation effects (RE)

therapeutic use (TU)

ultrastructure (UL)

Concept UI: M0556121
Scope Note: An inhibitory T-lymphocyte receptor that has specificity for CD274 ANTIGEN and PROGRAMMED CELL DEATH 1 LIGAND 2 PROTEIN. Signaling by the receptor limits T cell proliferation and INTERFERON GAMMA synthesis. The receptor also may play an essential role in the regulatory pathway that induces PERIPHERAL TOLERANCE.
Terms: Programmed Cell Death 1 Receptor Preferred Term
Term UI T788015
Date03/30/2011
LexicalTag NON
ThesaurusID NLM (2012); PD-1 Protein
Term UI T000999638
Date11/27/2019
LexicalTag NON
ThesaurusID NLM (2021); Programmed Cell Death 1 Protein
Term UI T787890
Date03/29/2011
LexicalTag NON
ThesaurusID NLM (2012); Antigens, CD279
Term UI T788016
Date03/30/2011
LexicalTag ABX
ThesaurusID NLM (2012); CD279 Antigen
Term UI T788017
Date03/30/2011
LexicalTag ABX
ThesaurusID NLM (2012); PD1 Receptor
Term UI T788018
Date03/30/2011
LexicalTag ABX
ThesaurusID NLM (2012); Programmed Cell Death Protein 1
Term UI T000999637
Date11/27/2019
LexicalTag NON
ThesaurusID NLM (2021); PD-1 Receptor
Term UI T788019
Date03/30/2011
LexicalTag ABX
ThesaurusID NLM (2012)

Programmed Cell Death 1 Receptor MeSH Descriptor Data 2024