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B7-H1 Antigen MeSH Descriptor Data 2022


MeSH Heading
B7-H1 Antigen
Tree Number(s)
D12.776.465.625
D12.776.467.150.300
D12.776.543.095.300
D23.050.301.285.400
D23.529.168.300
Unique ID
D060890
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D060890
Scope Note
An inhibitory B7 antigen that contains V-type and C2 type immunoglobulin domains. It has specificity for the T-CELL receptor PROGRAMMED CELL DEATH 1 PROTEIN and provides negative signals that control and inhibit T-cell responses. It is found at higher than normal levels on tumor cells, suggesting its potential role in TUMOR IMMUNE EVASION.
Entry Term(s)
Antigens, CD274
B7-H1 Immune Costimulatory Protein
B7H1 Immune Costimulatory Protein
CD274 Antigen
PD-L1 Costimulatory Protein
PD-L1 Protein
Programmed Cell Death 1 Ligand 1
Programmed Cell Death 1 Ligand 1 Protein
Programmed Death Ligand 1
Registry Number
0
Previous Indexing
Antigens, CD (2007-2011)
Antigens, CD80 (2001-2006)
Blood Proteins (2001-2005)
See Also
Immunoglobulin Domains
Public MeSH Note
2018; see ANTIGENS, CD274 2012-2017
History Note
2018 (2007)
Date Established
2012/01/01
Date of Entry
2011/06/24
Revision Date
2020/03/27
B7-H1 Antigen Preferred
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