- Concept UI
- M0028391
- Registry Numbers
- 0
- Scope Note
- Members of the tumor necrosis factor receptor superfamily with specificity for CD40 LIGAND. They are found on mature B-LYMPHOCYTES, some EPITHELIAL CELLS; and lymphoid DENDRITIC CELLS. Evidence suggests that CD40-dependent activation of B-cells is important for generation of memory B-cells within the germinal centers. Mutations in the CD40 antigen gene result in HYPER-IGM IMMUNODEFICIENCY SYNDROME, TYPE 3. Signaling of the receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
- Terms
-
CD40 Antigens
Preferred Term
Term UI
T056734
Date01/06/1995
LexicalTag
NON
ThesaurusID
NLM (1996)
-
Tumor Necrosis Factor Receptor Superfamily, Member 5
Term UI
T571726
Date02/06/2004
LexicalTag
NON
ThesaurusID
NLM (2005)
-
TNFRSF5 Receptor
Term UI
T572165
Date02/10/2004
LexicalTag
ACX
ThesaurusID
NLM (2005)
-
CD40 Antigen
Term UI
T056733
Date01/06/1995
LexicalTag
NON
ThesaurusID
NLM (1996)
-
Antigens, CD40
Term UI
T056735
Date01/01/1999
LexicalTag
ACX
ThesaurusID
NLM (1996)
-
CDw40 Antigen
Term UI
T056736
Date01/06/1995
LexicalTag
NON
ThesaurusID
NLM (1996)