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Dipeptidyl Peptidase 4 MeSH Descriptor Data 2022


MeSH Heading
Dipeptidyl Peptidase 4
Tree Number(s)
D08.811.277.656.350.350.126
D08.811.277.656.959.250
D23.050.301.264.894.160
D23.101.100.894.160
Unique ID
D018819
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D018819
Scope Note
A serine protease that catalyses the release of an N-terminal dipeptide. Several biologically-active peptides have been identified as dipeptidyl peptidase 4 substrates including INCRETINS; NEUROPEPTIDES; and CHEMOKINES. The protein is also found bound to ADENOSINE DEAMINASE on the T-CELL surface and is believed to play a role in T-cell activation.
Entry Term(s)
Adenosine Deaminase Complexing Protein 2
Antigens, CD26
CD26 Antigen
CD26 Antigens
Dipeptidyl-Peptidase IV
Registry Number
EC 3.4.14.5
Previous Indexing
Antigens, Differentiation, T-Lymphocyte (1990-1994)
Carrier Proteins (1978-1994)
Dipeptidyl Peptidases (1980-1994)
Public MeSH Note
2011; see CD26 ANTIGEN 1995-2010; CD26 ANTIGEN was indexed under ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1990-1994; DIPEPTIDYL PEPTIDASE IV was indexed under DIPEPTIDYL PEPTIDASES 1980-1994
History Note
2011(1998)
Entry Combination
antagonists & inhibitors:Dipeptidyl-Peptidase IV Inhibitors
Date Established
1995/01/01
Date of Entry
1994/05/27
Revision Date
2017/05/24
Dipeptidyl Peptidase 4 Preferred
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