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Cathepsin C MeSH Descriptor Data 2022


MeSH Heading
Cathepsin C
Tree Number(s)
D08.811.277.656.224.130
D08.811.277.656.262.186
D08.811.277.656.350.350.100
Unique ID
D020789
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D020789
Scope Note
A papain-like cysteine protease that has specificity for amino terminal dipeptides. The enzyme plays a role in the activation of several pro-inflammatory serine proteases by removal of their aminoterminal inhibitory dipeptides. Genetic mutations that cause loss of cathepsin C activity in humans are associated with PAPILLON-LEFEVRE DISEASE.
Entry Term(s)
Dipeptidyl Aminopeptidase I
Dipeptidyl Peptidase I
Dipeptidyl Transferase
Registry Number
EC 3.4.14.1
Previous Indexing
Dipeptidyl Peptidases (1984-1999)
Public MeSH Note
2010; see DIPEPTIDYL PEPTIDASE I 2000-2009; DIPEPTIDYL PEPTIDASE I was indexed under DIPEPTIDYL PEPTIDASES 1984-1999; CATHEPSINS 1981-1984
History Note
2010(1981)
Date Established
2000/01/01
Date of Entry
1999/11/05
Revision Date
2010/06/25
Cathepsin C Preferred
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