MeSH Browser

MeSH Heading: Dipeptidyl-Peptidase IV Inhibitors
Tree Number(s): D27.505.519.389.745.335; D27.505.696.422.500
Unique ID: D054873
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D054873
Scope Note: Compounds that suppress the degradation of INCRETINS by blocking the action of DIPEPTIDYL-PEPTIDASE IV. This helps to correct the defective INSULIN and GLUCAGON secretion characteristic of TYPE 2 DIABETES MELLITUS by stimulating insulin secretion and suppressing glucagon release.
Entry Term(s): DPP-4 Inhibitor; DPP-4 Inhibitors; DPP-IV Inhibitor; DPP-IV Inhibitors; DPP4 Inhibitor; DPP4 Inhibitors; Dipeptidyl Peptidase 4 Inhibitor; Dipeptidyl-Peptidase 4 Inhibitor; Dipeptidyl-Peptidase 4 Inhibitors; Dipeptidyl-Peptidase IV Inhibitor; Gliptin; Gliptins
Registry Numbers: 0
Public MeSH Note: 2008
History Note: 2008
Date Established: 2008/01/01
Date of Entry: 2007/07/09
Revision Date: 2020/05/27

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

economics (EC)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

urine (UR)

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Molecular Mechanisms of Pharmacological Action [D27.505.519]
    - Enzyme Inhibitors [D27.505.519.389]
      - Protease Inhibitors [D27.505.519.389.745]
        
        Angiotensin-Converting Enzyme Inhibitors [D27.505.519.389.745.085]
        
        Cysteine Proteinase Inhibitors [D27.505.519.389.745.325]
        
        Dipeptidyl-Peptidase IV Inhibitors [D27.505.519.389.745.335]
        
        Matrix Metalloproteinase Inhibitors [D27.505.519.389.745.610]
        
        Proteasome Inhibitors [D27.505.519.389.745.705]
        
        Renin Inhibitors [D27.505.519.389.745.753]
        
        Serine Proteinase Inhibitors [D27.505.519.389.745.800]
        
        Viral Protease Inhibitors [D27.505.519.389.745.900]

Chemical Actions and Uses [D27]
- Pharmacologic Actions [D27.505]
  - Physiological Effects of Drugs [D27.505.696]
    - Hypoglycemic Agents [D27.505.696.422]

Dipeptidyl-Peptidase IV Inhibitors Preferred

Concept UI: M0508515
Registry Numbers: 0
Scope Note: Compounds that suppress the degradation of INCRETINS by blocking the action of DIPEPTIDYL-PEPTIDASE IV. This helps to correct the defective INSULIN and GLUCAGON secretion characteristic of TYPE 2 DIABETES MELLITUS by stimulating insulin secretion and suppressing glucagon release.
Terms: Dipeptidyl-Peptidase IV Inhibitors Preferred Term
Term UI T695078
Date04/06/2007
LexicalTag NON
ThesaurusID NLM (2008); DPP-4 Inhibitor
Term UI T000999829
Date11/29/2019
LexicalTag NON
ThesaurusID NLM (2021); DPP-IV Inhibitor
Term UI T000999830
Date11/29/2019
LexicalTag NON
ThesaurusID NLM (2021); DPP-4 Inhibitors
Term UI T000999825
Date11/29/2019
LexicalTag ABX
ThesaurusID NLM (2021); DPP-IV Inhibitors
Term UI T000999826
Date11/29/2019
LexicalTag ABX
ThesaurusID NLM (2021); DPP4 Inhibitors
Term UI T000999828
Date11/29/2019
LexicalTag NON
ThesaurusID NLM (2021); Dipeptidyl Peptidase 4 Inhibitor
Term UI T000997581
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Dipeptidyl-Peptidase IV Inhibitor
Term UI T000997582
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Dipeptidyl-Peptidase 4 Inhibitor
Term UI T000997583
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021); Dipeptidyl-Peptidase 4 Inhibitors
Term UI T766315
Date02/26/2010
LexicalTag NON
ThesaurusID NLM (2011); Gliptins
Term UI T695079
Date04/06/2007
LexicalTag NON
ThesaurusID NLM (2008); DPP4 Inhibitor
Term UI T001008522
Date02/24/2020
LexicalTag NON
ThesaurusID NLM (2021); Gliptin
Term UI T000997584
Date11/19/2019
LexicalTag NON
ThesaurusID NLM (2021)

Dipeptidyl-Peptidase IV Inhibitors MeSH Descriptor Data 2025