CD56 Antigen MeSH Descriptor Data 2025

MeSH Heading: CD56 Antigen
Tree Number(s): D09.400.430.890.200.250.520.156; D12.776.395.550.200.250.520.156; D12.776.543.550.200.250.520.156; D23.050.301.264.894.156; D23.050.301.350.250.520.156; D23.101.100.894.156
Unique ID: D019002
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D019002
Annotation: for hematodermic CD4/CD56 neoplasm use LYMPHOMA, NON-HODGKIN
Scope Note: The 140 kDa isoform of NCAM (neural cell adhesion molecule) containing a transmembrane domain and short cytoplasmic tail. It is expressed by all lymphocytes mediating non-MHC restricted cytotoxicity and is present on some neural tissues and tumors.
Entry Term(s): Antigens, CD56; CD56 Antigens; Leu-19 Antigen; NKH-1 Antigen
Registry Numbers: 0
Previous Indexing: Antigens, CD (1990-1995); Antigens, Differentiation, T-Lymphocyte (1988-1995)
Public MeSH Note: 2018; see ANTIGENS, CD56 1996-2017 and NKH-1 ANTIGEN 1988-95; NKH-1 ANTIGEN was indexed under ANTIGENS, CD 1990-95; and under ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE 1988-95
History Note: 2018 (1988)
Date Established: 1996/01/01
Date of Entry: 1995/05/26
Revision Date: 2023/03/16

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Carbohydrates [D09]
- Glycoconjugates [D09.400]
  - Glycoproteins [D09.400.430]
    - Membrane Glycoproteins [D09.400.430.890]
      - Cell Adhesion Molecules [D09.400.430.890.200]
        
        Cell Adhesion Molecules, Neuronal [D09.400.430.890.200.250]
        
        Neural Cell Adhesion Molecules [D09.400.430.890.200.250.520]
        
        CD56 Antigen [D09.400.430.890.200.250.520.156]
        
        Neural Cell Adhesion Molecule L1 [D09.400.430.890.200.250.520.578]
        
        Neurocan [D09.400.430.890.200.250.520.789]
        
        Neuroligins [D09.400.430.890.200.250.520.894]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Glycoproteins [D12.776.395]
    - Membrane Glycoproteins [D12.776.395.550]
      - Cell Adhesion Molecules [D12.776.395.550.200]
        
        Cell Adhesion Molecules, Neuronal [D12.776.395.550.200.250]
        
        Neural Cell Adhesion Molecules [D12.776.395.550.200.250.520]
        
        CD56 Antigen [D12.776.395.550.200.250.520.156]
        
        Neural Cell Adhesion Molecule L1 [D12.776.395.550.200.250.520.578]
        
        Neurocan [D12.776.395.550.200.250.520.789]
        
        Neuroligins [D12.776.395.550.200.250.520.894]

Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
  - Membrane Proteins [D12.776.543]
    - Membrane Glycoproteins [D12.776.543.550]
      - Cell Adhesion Molecules [D12.776.543.550.200]
        
        Cell Adhesion Molecules, Neuronal [D12.776.543.550.200.250]
        
        Neural Cell Adhesion Molecules [D12.776.543.550.200.250.520]
        
        CD56 Antigen [D12.776.543.550.200.250.520.156]
        
        Neural Cell Adhesion Molecule L1 [D12.776.543.550.200.250.520.578]
        
        Neurocan [D12.776.543.550.200.250.520.789]
        
        Neuroligins [D12.776.543.550.200.250.520.894]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Antigens, Differentiation [D23.050.301.264]
      - Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
        
        Antigens, CD1 [D23.050.301.264.894.080]
        
        CD2 Antigens [D23.050.301.264.894.090]
        
        T Lineage-Specific Activation Antigen 1 [D23.050.301.264.894.093]
        
        CD3 Complex [D23.050.301.264.894.095]
        
        CD4 Antigens [D23.050.301.264.894.100]
        
        CD5 Antigens [D23.050.301.264.894.101]
        
        Antigens, CD7 [D23.050.301.264.894.107]
        
        CD8 Antigens [D23.050.301.264.894.108]
        
        CD13 Antigens [D23.050.301.264.894.113]
        
        CD18 Antigens [D23.050.301.264.894.118]
        
        Lymphocyte Activation Gene 3 Protein [D23.050.301.264.894.121]
        
        Thy-1 Antigens [D23.050.301.264.894.123]
        
        Tumor Necrosis Factor Receptor Superfamily, Member 7 [D23.050.301.264.894.127]
        
        CD28 Antigens [D23.050.301.264.894.128]
        
        CD56 Antigen [D23.050.301.264.894.156]
        
        CD57 Antigens [D23.050.301.264.894.157]
        
        CTLA-4 Antigen [D23.050.301.264.894.158]
        
        Dipeptidyl Peptidase 4 [D23.050.301.264.894.160]
        
        Inducible T-Cell Co-Stimulator Protein [D23.050.301.264.894.580]
        
        Programmed Cell Death 1 Receptor [D23.050.301.264.894.790]

Biological Factors [D23]
- Antigens [D23.050]
  - Antigens, Surface [D23.050.301]
    - Cell Adhesion Molecules [D23.050.301.350]
      - Cell Adhesion Molecules, Neuronal [D23.050.301.350.250]
        
        Neural Cell Adhesion Molecules [D23.050.301.350.250.520]
        
        CD56 Antigen [D23.050.301.350.250.520.156]
        
        Neural Cell Adhesion Molecule L1 [D23.050.301.350.250.520.578]
        
        Neurocan [D23.050.301.350.250.520.789]
        
        Neuroligins [D23.050.301.350.250.520.894]

Biological Factors [D23]
- Biomarkers [D23.101]
  - Antigens, Differentiation [D23.101.100]
    - Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]

CD56 Antigen Preferred

Concept UI: M0028376
Registry Numbers: 0
Scope Note: The 140 kDa isoform of NCAM (neural cell adhesion molecule) containing a transmembrane domain and short cytoplasmic tail. It is expressed by all lymphocytes mediating non-MHC restricted cytotoxicity and is present on some neural tissues and tumors.
Terms: CD56 Antigen Preferred Term
Term UI T056658
Date12/28/1994
LexicalTag NON
ThesaurusID NLM (1996); NKH-1 Antigen
Term UI T056657
Date12/29/1994
LexicalTag NON
ThesaurusID NLM (1996); CD56 Antigens
Term UI T056659
Date12/28/1994
LexicalTag NON
ThesaurusID NLM (1996); Antigens, CD56
Term UI T056660
Date01/01/1999
LexicalTag ACX
ThesaurusID NLM (1996); Leu-19 Antigen
Term UI T056661
Date12/29/1994
LexicalTag NON
ThesaurusID NLM (1996)

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